Manti co-founded  Cimex Medical Innovations (formerly Cimex Biotech LC) in 1996 with Dr. Michael Haas. With a goal of diversifying their venture portfolio into the biomedical field, this newly established, innovative company was an obvious choice. Cimex was established to vett and review multiple medical-intended devices that had yet to be introduced to the public market. The company accomplished this through commercial and medical research for the development of medical products in the foot care, emergency medicine, and cardiovascular areas of healthcare. Cimex has been recognized as a pioneer in cryogenic surgical applications, as well as cardiac assist device research. While the successful Cryopen device is a primary focus of Cimex, they continually research other successful opportunities.